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antroposcopio
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- The Diagnosis Trap septiembre 23, 2022Let me explain something about me: When I was 12, I started having panic attacks, brought on by fears that I couldn’t shake, even though I knew they were irrational. I was terrified, for example, that I’d become depressed—but I’d never been depressed before, and didn’t feel depressed. My junior high school devoted a series […]Jordan Kisner
- Universe Price Tiers septiembre 6, 2022
- Another dismissal of biological facts that go against ideology: The NYT claims that “maternal instinct” is a misogynistic myth. septiembre 3, 2022UPDATE: In a comment below, Randolph Nesse, one of the founders of “Darwinian medicine,” cites a book I’d forgotten: If only everyone interested in this topic could read “Mother Nature: Maternal Instincts and How They Shape the Human Species”, Sarah Hrdy’s 2020 book on the topic. And if only the NY Times would review such […]
- Prevalence and Risk Factor Profiles for Chronic Axonal Polyneuropathy in the General Population agosto 27, 2022Neurology. 2022 Aug 25:10.1212/WNL.0000000000201168. doi: 10.1212/WNL.0000000000201168. Online ahead of print.ABSTRACTBACKGROUND AND OBJECTIVES: Chronic axonal polyneuropathy is a common disease with increasing prevalence with age. It majorly impacts quality of life and leads to difficulties with various activities. Persons with polyneuropathy often not seek medical care and thus the societal burden of disease is likely underreported. […]Noor E Taams
- Plexus MRI helps distinguish the immune-mediated neuropathies MADSAM and MMN agosto 27, 2022J Neuroimmunol. 2022 Aug 18;371:577953. doi: 10.1016/j.jneuroim.2022.577953. Online ahead of print.ABSTRACTBACKGROUND: Among immune-mediated neuropathies, clinical-electrophysiological overlap exists between multifocal acquired demyelinating sensory and motor neuropathy (MADSAM) and multifocal motor neuropathy (MMN). Divergent immune pathogenesis, immunotherapy response, and prognosis exist between these two disorders. MRI reports have not shown distinction of these disorders, but biopsy confirmation […]Grayson Beecher
- Two complementary features of humoral immune memory confer protection against the same or variant antigens agosto 27, 2022Proc Natl Acad Sci U S A. 2022 Sep 13;119(37):e2205598119. doi: 10.1073/pnas.2205598119. Epub 2022 Aug 25.ABSTRACTThe humoral immune response, a key arm of adaptive immunity, consists of B cells and their products. Upon infection or vaccination, B cells undergo a Darwinian evolutionary process in germinal centers (GCs), resulting in the production of antibodies and memory […]Matthew Van Beek
- Treatment of Chronic Inflammatory Demyelinating Polyneuropathy agosto 27, 2022Muscle Nerve. 2022 Aug 22. doi: 10.1002/mus.27709. Online ahead of print.ABSTRACTChronic inflammatory demyelinating polyneuropathy (CIDP) is a chronic peripheral polyneuropathy that results in disability through immune mediated nerve injury, but which not uncommonly has residual and irreversible neurologic deficits after the active inflammatory component of the disorder has been treated. Management of the condition entails […]Jeffrey A Allen
- Autoimmune nodopathies, an emerging diagnostic category agosto 27, 2022Curr Opin Neurol. 2022 Aug 22. doi: 10.1097/WCO.0000000000001107. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: In the last decade, antibodies targeting cell adhesion molecules of the node of Ranvier were described in patients with autoimmune neuropathies. These nodal/paranodal antibodies associate with specific clinicopathological features that are different from classical chronic inflammatory demyelinating polyneuropathy (CIDP). In this […]Lorena Martín-Aguilar
- Pragmatismo modélico agosto 26, 2022Essentially, all models are wrong, but some are useful.George E. P. Box En esencia, esa frase resume una verdad universal de la que está imbuido todo el conocimiento que la humanidad posee sobre el mundo. Sí, todo nuestro conocimiento es parcial, imperfecto, y, en consecuencia, erróneo: susceptible de ser perfeccionado. Pero eso no equivale a […]Jose Alcántara
- High-dimensional investigation of the cerebrospinal fluid to explore and monitor CNS immune responses agosto 21, 2022Genome Med. 2022 Aug 17;14(1):94. doi: 10.1186/s13073-022-01097-9.ABSTRACTThe cerebrospinal fluid (CSF) features a unique immune cell composition and is in constant contact with the brain borders, thus permitting insights into the brain to diagnose and monitor diseases. Recently, the meninges, which are filled with CSF, were identified as a neuroimmunological interface, highlighting the potential of exploring […]Michael Heming
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marzo 17, 2012 at 6:41 pm
aí, aí, yo también me uno
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